MYC dysregulation by enhancer duplications in pediatric cancers.

(A) Copy number gains from BALL, TALL, and AML over the 2 Mb region spanning MYC (yellow, left), and two enhancers (N-ME: cyan, BENC: gray).

(B) Detailed assay results of NALM6, including in-situ Hi-C (heatmap), stranded total RNA-seq (blue for forward strand, red for reverse strand), H3K27ac ChIP-seq (green), ATAC-seq (black), and Capture-C using MYC promoter as bait (purple).