Custom MYC variants
BigWig, stranded coverage
Tumor-normal allelic imbalance
ChromHMM + gene expression, aka PGV
Differential gene expression as MA and Volcano plots, with RNA-seq coverage
Single-cell RNAseq tSNE
Illustrating multiple mechanisms for oncogene TAL1 activation in Cohort View.
Matrix View reviews mutual-exclusive or co-mutation pattern, for association with patient outcome.
Visualize multi-omics data with dynamic range in Sample View.
Sample View of interchromsomal rearrangement leading to MYC dysregulation by enhancer-hijacking.
Assessing aberrant splicing in CREBBP caused by somatic splice site variants.
MYC dysregulation by enhancer duplications in pediatric cancers.
Cohort View shows different mutation mechanisms causing loss-of-function in tumor suppressors.
Cohort View enables associating mutation or expression data with patient outcomes.
B-ALL shows diverse alterations targeting CREBBP RING domain.
Previously unreported cases of likely MYC enhancer duplication/amplification in pediatric tumors and cell line.
In-situ Hi-C shows MYC interaction with duplicated enhancers in NALM6 and NALM16.
Phased sequencing coverage in NALM6.
DUX4 but not NOTCH1 likely binds at N-ME in NALM6.
CDKN2A/2B focal deletion and sequence mutations from adult diffuse large B-cell lymphoma (DLBC)
TERT sequence mutations in adult cutaneous melanoma (SKCM).
RNA-seq tSNE plot of the pan-BALL study